fredag 30 juni 2017

We think Propoxyphene (Darvon & Darvocet) is a big part of the present - and worst heroin-epidemic ever.


Dear Sirs,

Please go to this link, I tell about the purpose of the following letter http://bit.ly/2tACv7Y

Darvon&Darvocet are important parts of the heroin-epidemic of today. They were on the US market for 53 years
---------------------------------------------------------------------------------
I know and understand that you are very busy working with the heroin-epidemic, and how the opiates affected 100,000s people. There is a lot of discussion in the United States about the analgesic preparations Oxycodone and Fentanyl. These preparations were introduced on the American market in the mid 1990s.

We have written seven scientific articles about DXP, we wrote and defended two doctoral dissertation – one at the Forensic Medicine Department at the University of Uppsala, Sweden (2000), the other at the Nordic School of Public Health in Gothenburg, Sweden (2001).

“Studies on Dextropropoxyphene with Special Reference to Dependence Among Chronic Pain Patients, Classification of the Manner of Death in Fatal Poisonings Victim” by Birgitta Jonasson and “Studies on the use of dextropropoxyphene from the aspect of public health. Influence of a regulatory framework” by Ulf Jonasson. The first dissertation is all in English and the other is written in Swedish.

To reach out in the Society we wrote a popular book “Fatalities due to use or misuse of painkillers”, which was published both in Swedish and in English. We – Birgitta and Ulf Jonasson - wrote these books in collaboration with The National Board of Forensic Medicine in Sweden.

Our main data came from the years 1992-1996, in the dissertations and we updated the data for the years 1992-2004.

One main results was that the DXP caused fatal poisoned for around 200 persons every year – during the investigated years. Sweden had during these years a population of around 8,8 million inhabitants
----------------------------------------------------------------
Thanks to INCB (The International Narcotic Control Board) in Vienna we have statistical data of the consumption of DXP from year 1982 - 2015., and Oxycodone, Hydrocodona and Fentanyl. DXP  was was banned 2010.

Consumption of Oxycodone, Hydrocodone, Fentanyl and Propoxyohene 

( Source. INCB http://bit.ly/2tg68em  - last figures page 69 of 120)

Oxycodone:

1999-2015 = 17 years. 742 082 kg/17 years= average/year: 43 652 kg

Hydrocodone:

1999-2015 = 17 years. 524 754 kr/17 years= average/year: 30 869 kg

Fentanyl:

1996-2015 = 20 years. 7559 kg/20 years = average/year: 378 kg

Propoxyphene:

1980-2010 = 32 years. 2 761 310 kg/32 years=average/year 82 853 kg

---------------------------------------------------------

We have also estimated numbers of fatalities due to poisoning to death by DXP and we have comparen one unit - FDLE ( medical examiners) with another unit - LA County ( coroners)

Data from Florida Department of Law Enforcement (FDLE) – Drugs identified in Decease Persons by Florida Medical Examiner during the years 2001-2012.

We have figures from” the numbers of deaths” for every year, “drug related deaths”, “total occurrences of Propoxyphene” and “Cause of death” and “Present”, death with DXP +other drugs, death with DXP only and Frequency of Occurrences of Drugs Decedents.

These data have literally taken ten-twelve years to collect.

We have also collected data from Los Angeles County Department of Coroner Annual Report

1. Prescriptions Drug Categories (Drugs by Classification) 2003-2010

The drugs were: Antidepressant, Antihistamines, Antipsychyotics, Muscle Relaxants, Sedative Hypnotic and Narcotic Analgesics (which means all kind of painkillers. You are not able to say if it is propoxyphene or not)

2. Numbers of Cases with Drugs Detected by Mode (2003-2009)

The Drugs were; Alcohol, Marijuana, Cocaine, Meth, Heroine, Phen. and Club Drugs. Note: In the LA County the were  not looking for propoxyphene.
---------------------------------------------------------------------------------------------
I sent a tweet to Dr Tom Frieden at CDC. His answer in very interesting. If you don´t look for Propoxyphene you will not find any. 


LA County is the largest in US, but during the years 2003-2010 they didn´t have any cases with DXP. During these 8 years the consumption of DXP in USA was an average of 82 853 x 8 = 662 824 kg

We have also interesting prescription data for Propoxyphene for the years 2000-2010 (that is 11 years) . A total of 244 828 000 prescriptions during these years - per year 22 257 090 and the consumption was 923 635 kilograms for the 11 years

We have estimated that the number of fatal poisons during these approximately 53 years can be as many as about 300,000 people,



Ulf Jonasson, PhD

Yours faithfully

Ulf Jonasson
---------------------------------------------------------
Doctor in Public Health (PhD) and Journalist
Stortorget 6, SE-641 30 Katrineholm, Sweden

https://www.facebook.com/ulf.jonasson.54
http://jonassonulf.blogspot.se/
https://twitter.com/JonassonPhD
--------------------------------------------------------



Inga kommentarer:

Skicka en kommentar